{"id":113,"date":"2023-11-01T15:30:52","date_gmt":"2023-11-01T15:30:52","guid":{"rendered":"https:\/\/research.dental.uw.edu\/comrc\/?page_id=113"},"modified":"2023-11-16T22:11:45","modified_gmt":"2023-11-16T22:11:45","slug":"research","status":"publish","type":"page","link":"https:\/\/research.dental.uw.edu\/comrc\/research\/","title":{"rendered":"Research"},"content":{"rendered":"<h2>NIH Awards<\/h2>\n<p><strong>Mechanisms underlying the variation in rate and levels of gingival inflammatory responses among the human population<\/strong><br \/>\nNIH\/NIDCR R01 Registered Clinical Trial:\u00a0 <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05968742?term=NCT05968742&amp;rank=1\">Experimental Gingivitis Model (Clinicaltrials.gov)<\/a><\/p>\n<p><strong>Resolving Oral Bacteria Interactions with a High-Throughput Low-Cost Single-Cell Transcriptomics Approach<\/strong><br \/>\nNIH\/NIDCR R21: University of Washington and Institute for Systems Biology Collaboration<\/p>\n<h2>Contracts<\/h2>\n<p>Colgate Palmolive Awards<\/p>\n<p>Associated Publications<\/p>\n<p>Fine, N., Barbour, A., Kaura, K., <strong>Kerns, K.A<\/strong>., Chen, D., Trivedi, H.M., Gomez, J., Sabharwal, A., <strong>McLean, J.S<\/strong>., Darveau, R.P. &amp; Glogauer, M. Effects of a stabilized stannous fluoride dentifrice on clinical, immunomodulatory, and microbial outcomes in a human experimental gingivitis model. <a title=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/37885337\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/37885337\" target=\"_blank\" rel=\"noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/37885337<\/a> <em>J Periodontol<\/em>, <strong>2023<\/strong><\/p>\n<p><strong>Kerns, K.A.<\/strong>, Bamashmous, S., <strong>Hendrickson, E.L.<\/strong>, Kotsakis, G.A., Leroux, B.G., Daubert, D.D., Roberts, F.A., Chen, D., Trivedi, H.M., Darveau, R.P. &amp; <strong>McLean, J.S<\/strong>. <a href=\"https:\/\/www.pnas.org\/doi\/abs\/10.1073\/pnas.2306020120\">Localized microbially induced inflammation influences distant healthy tissues in the human oral cavity<\/a>.<em> Proceedings of the National Academy of Sciences<\/em> 120: e2306020120, <strong>2023<\/strong><\/p>\n<p>Bamashmous, S., Kotsakis, G. A., Kerns, K. A., Leroux, B. G., Zenobia, C., Chen, D., Trivedi, H. M., <strong>McLean, J. S*.<\/strong>, &amp; Darveau, R. P. (<strong>2021<\/strong>). Human variation in gingival inflammation. <em>Proceedings of the National Academy of Sciences of the United States of America<\/em>, <em>118<\/em>(27), e2012578118.<a href=\"https:\/\/doi.org\/10.1073\/pnas.2012578118\"> https:\/\/doi.org\/10.1073\/pnas.2012578118<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>NIH Awards Mechanisms underlying the variation in rate and levels of gingival inflammatory responses among the human population NIH\/NIDCR R01 Registered Clinical Trial:\u00a0 Experimental Gingivitis Model (Clinicaltrials.gov) Resolving Oral Bacteria Interactions with a High-Throughput Low-Cost Single-Cell Transcriptomics Approach NIH\/NIDCR R21: University of Washington and Institute for Systems Biology Collaboration Contracts Colgate Palmolive Awards Associated Publications Fine, N., Barbour, A., Kaura, K., Kerns, K.A., Chen, D., Trivedi, H.M., Gomez, J., Sabharwal, A., McLean, J.S., Darveau, R.P. &amp; Glogauer, M. Effects of&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-113","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Research - Clinical Oral Microbiome Center<\/title>\n<meta name=\"description\" content=\"The goal of the Clinical Oral Microbiome Research Center (COMRC) is to study the microbial and host determinants of oral health.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/research.dental.uw.edu\/comrc\/research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research - 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