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Clinical Oral Microbiome Research Center


NIH Awards

Mechanisms underlying the variation in rate and levels of gingival inflammatory responses among the human population
NIH/NIDCR R01 Registered Clinical Trial:  Experimental Gingivitis Model (

Resolving Oral Bacteria Interactions with a High-Throughput Low-Cost Single-Cell Transcriptomics Approach
NIH/NIDCR R21: University of Washington and Institute for Systems Biology Collaboration


Colgate Palmolive Awards

Associated Publications

Fine, N., Barbour, A., Kaura, K., Kerns, K.A., Chen, D., Trivedi, H.M., Gomez, J., Sabharwal, A., McLean, J.S., Darveau, R.P. & Glogauer, M. Effects of a stabilized stannous fluoride dentifrice on clinical, immunomodulatory, and microbial outcomes in a human experimental gingivitis model. J Periodontol, 2023

Kerns, K.A., Bamashmous, S., Hendrickson, E.L., Kotsakis, G.A., Leroux, B.G., Daubert, D.D., Roberts, F.A., Chen, D., Trivedi, H.M., Darveau, R.P. & McLean, J.S. Localized microbially induced inflammation influences distant healthy tissues in the human oral cavity. Proceedings of the National Academy of Sciences 120: e2306020120, 2023

Bamashmous, S., Kotsakis, G. A., Kerns, K. A., Leroux, B. G., Zenobia, C., Chen, D., Trivedi, H. M., McLean, J. S*., & Darveau, R. P. (2021). Human variation in gingival inflammation. Proceedings of the National Academy of Sciences of the United States of America, 118(27), e2012578118.